Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome

RC Simpson, ER Shanahan, M Batten, ILM Reijers… - Nature medicine, 2022 - nature.com
The gut microbiota shapes the response to immune checkpoint inhibitors (ICIs) in cancer,
however dietary and geographic influences have not been well-studied in prospective trials …

Differences in gut microbiota in patients with vs without inflammatory bowel diseases: a systematic review

R Pittayanon, JT Lau, GI Leontiadis, F Tse, Y Yuan… - Gastroenterology, 2020 - Elsevier
Background & Aims Altering the intestinal microbiota has been proposed as a treatment for
inflammatory bowel diseases (IBDs), but there are no established associations between …

Implication of intestinal barrier dysfunction in gut dysbiosis and diseases

C Stolfi, C Maresca, G Monteleone, F Laudisi - Biomedicines, 2022 - mdpi.com
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

The gut microbiota in the pathogenesis and therapeutics of inflammatory bowel disease

T Zuo, SC Ng - Frontiers in microbiology, 2018 - frontiersin.org
In the twenty first century, the changing epidemiology of inflammatory bowel disease (IBD)
globally with increasing disease incidence across many countries relates to the altered gut …

Dynamics of the human gut microbiome in inflammatory bowel disease

J Halfvarson, CJ Brislawn, R Lamendella… - Nature …, 2017 - nature.com
Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic
need for increased medication and sometimes even surgery. The aetiology of IBD is partly …

The promise of the gut microbiome as part of individualized treatment strategies

DA Schupack, RAT Mars, DH Voelker… - Nature reviews …, 2022 - nature.com
Variability in disease presentation, progression and treatment response has been a central
challenge in medicine. Although variability in host factors and genetics are important, it has …

Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches

RB Sartor, GD Wu - Gastroenterology, 2017 - Elsevier
Intestinal microbiota are involved in the pathogenesis of Crohn's disease, ulcerative colitis,
and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses …

Inflammation, antibiotics, and diet as environmental stressors of the gut microbiome in pediatric Crohn's disease

JD Lewis, EZ Chen, RN Baldassano, AR Otley… - Cell host & …, 2015 - cell.com
Abnormal composition of intestinal bacteria—" dysbiosis"—is characteristic of Crohn's
disease. Disease treatments include dietary changes and immunosuppressive anti-TNFα …