Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …

DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Introduction 3. Germ Cell Apoptosis 4. Sperm Apoptosis 5. Apoptosis in cryptorchid testis 6.
Oxidative stress and apoptosis 7. Apoptosis and male infertility 8. Apoptosis and male …

Evidence suggests that disturbing the balance between reactive oxygen species levels and
antioxidant contents in seminal plasma leads to oxidative stress resulting in male infertility …

Sperm is not a simple carrier of paternal genetic information but its role extends clearly
beyond fertilization. Integrity of sperm genome is an essential pre-requisite for birth of …

Sperm cells can be damaged during the semen cryopreservation process, decreasing their
fertilizing ability. Physical damage and oxidative stress may occur during the freeze–thawing …

Reactive oxygen species (ROS) are essential for sperm physiological functions such as
capacitation, hyperactivation, and acrosome reaction, on the one hand, and for stimulating …

The fallopian tube, or oviduct, is no longer considered merely a conduit that joins the uterine
horns and the ovaries, being recognised as a venue for the capacitation of spermatozoa and …

Infertility affects about 15 per cent married couples half of which may be attributed to men
with low sperm motility (asthenozoospermia), low sperm count (oligozoospermia) or …