Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …

Historically, plants have been sought after as bio-factories for the production of diverse
chemical compounds that offer a multitude of possibilities to cure diseases. To combat the …

Due to the hugely important roles of neurotransmitter acetylcholine (ACh) and amyloid-β
(Aβ) in the pathogenesis of Alzheimer's disease (AD), the development of multi-target …

For the potential therapy of Alzheimer's disease (AD), butyrylcholinesterase (BChE) has
gradually gained worldwide interest in the progression of AD. This study used a …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting mental
ability and interrupts neurocognitive functions. Treating multifactorial conditions of AD with a …

In this research, a series of coumarin-based scaffolds linked to pyridine derivatives via a
flexible aliphatic linkage were synthesized and assessed as multifunctional anti-AD agents …

Alzheimer's disease (AD) is a neurodegenerative disease and one of the leading causes of
progressive dementia, affecting 50 million people worldwide. Many pathogenic processes …

Since the report of “a peculiar severe disease process of the cerebral cortex” by Alois
Alzheimer in 1906, it was considered to be a rare condition characterized by loss of …

With the aim to combat a multi-faceted neurodegenerative Alzheimer's disease (AD), a
series of carbazole-based semicarbazide and hydrazide derivatives were designed …

Background: Neurological disorders are composed of several diseases that affect the central
and peripheral nervous system; among these are neurodegenerative diseases, which lead …