Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Control of the structure and function of three-dimensional multicellular tissues depends
critically on the spatial and temporal coordination of cellular physical properties, yet the …

Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …

Automated microscopy has given researchers access to great amounts of live cell imaging
data from in vitro and in vivo experiments. Much focus has been put on extracting cell tracks …

Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or
rigidity transition. How cells control such phase transitions is, however, unknown. Here we …

The process in which locally confined epithelial malignancies progressively evolve into
invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a …

Morphological changes during development, tissue repair, and disease largely rely on
coordinated cell movements and are controlled by the tissue environment. Epithelial cell …

Morphogenesis requires dynamic coordination between cell–cell adhesion and the
cytoskeleton to allow cells to change shape and move without losing tissue integrity. We …

Collective cell migration is an essential process throughout the lives of multicellular
organisms, for example in embryonic development, wound healing and tumour metastasis …

The formation of self-organized patterns is key to the morphogenesis of multicellular
organisms, although a comprehensive theory of biological pattern formation is still lacking …