Chromatin accessibility: a window into the genome

M Tsompana, MJ Buck - Epigenetics & chromatin, 2014 - Springer
Transcriptional activation throughout the eukaryotic lineage has been tightly linked with
disruption of nucleosome organization at promoters, enhancers, silencers, insulators and …

Uncovering the roles of rare variants in common disease through whole-genome sequencing

ET Cirulli, DB Goldstein - Nature Reviews Genetics, 2010 - nature.com
Although genome-wide association (GWA) studies for common variants have thus far
succeeded in explaining only a modest fraction of the genetic components of human …

Integrative genomics viewer

JT Robinson, H Thorvaldsdóttir, W Winckler… - Nature …, 2011 - nature.com
Rapid improvements in sequencing and array-based platforms are resulting in a flood of
diverse genome-wide data, including data from exome and whole-genome sequencing …

Tablet—next generation sequence assembly visualization

I Milne, M Bayer, L Cardle, P Shaw, G Stephen… - …, 2010 - academic.oup.com
Tablet is a lightweight, high-performance graphical viewer for next-generation sequence
assemblies and alignments. Supporting a range of input assembly formats, Tablet provides …

Uncovering the complexity of transcriptomes with RNA‐Seq

V Costa, C Angelini, I De Feis… - BioMed Research …, 2010 - Wiley Online Library
In recent years, the introduction of massively parallel sequencing platforms for Next
Generation Sequencing (NGS) protocols, able to simultaneously sequence hundred …

Viral suppressors of RNA silencing

J Burgyán, Z Havelda - Trends in plant science, 2011 - cell.com
The infection and replication of viruses in the host induce diverse mechanisms for combating
viral infection. One of the best-studied antiviral defence mechanisms is based on RNA …

Principles of transcriptome analysis and gene expression quantification: an RNA‐seq tutorial

JBW Wolf - Molecular ecology resources, 2013 - Wiley Online Library
Genome‐wide analyses and high‐throughput screening was long reserved for biomedical
applications and genetic model organisms. With the rapid development of massively parallel …

A glimpse into past, present, and future DNA sequencing

M Morey, A Fernández-Marmiesse… - Molecular genetics and …, 2013 - Elsevier
Current advances in DNA sequencing technologies are dropping down sequencing cost
while increasing throughput at a pace never shown before. Past-decade great milestones …

A new grapevine virus discovered by deep sequencing of virus-and viroid-derived small RNAs in Cv Pinot gris

A Giampetruzzi, V Roumi, R Roberto, U Malossini… - Virus research, 2012 - Elsevier
Field symptoms of chlorotic mottling and leaf deformations were observed on the cv Pinot
gris (PG) in the Trentino region (Italy). Extensive assays excluded the presence of widely …

The ocean sampling day consortium

A Kopf, M Bicak, R Kottmann, J Schnetzer, I Kostadinov… - Gigascience, 2015 - Springer
Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …