Bacterial antibiotic resistance: the most critical pathogens

G Mancuso, A Midiri, E Gerace, C Biondo - Pathogens, 2021 - mdpi.com
Antibiotics have made it possible to treat bacterial infections such as meningitis and
bacteraemia that, prior to their introduction, were untreatable and consequently fatal …

Antibiotic resistance: one health one world outlook

B Aslam, M Khurshid, MI Arshad… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotic resistance (ABR) is a growing public health concern worldwide, and it is now
regarded as a critical One Health issue. One Health's interconnected domains contribute to …

The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

[HTML][HTML] The role of vaccines in combatting antimicrobial resistance

F Micoli, F Bagnoli, R Rappuoli, D Serruto - Nature Reviews …, 2021 - nature.com
The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Antibiotic resistance and persistence—Implications for human health and treatment perspectives

M Huemer, S Mairpady Shambat, SD Brugger… - EMBO …, 2020 - embopress.org
Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Antimicrobial stewardship: fighting antimicrobial resistance and protecting global public health

MAA Majumder, S Rahman, D Cohall… - Infection and drug …, 2020 - Taylor & Francis
Antimicrobial resistance (AMR) is a serious threat to global public health. It increases
morbidity and mortality, and is associated with high economic costs due to its health care …

Sulfonamide drugs: Structure, antibacterial property, toxicity, and biophysical interactions

A Ovung, J Bhattacharyya - Biophysical reviews, 2021 - Springer
Sulfonamide (or sulphonamide) functional group chemistry (SN) forms the basis of several
groups of drug. In vivo sulfonamides exhibit a range of pharmacological activities, such as …

Antimicrobial resistance: implications and costs

P Dadgostar - Infection and drug resistance, 2019 - Taylor & Francis
Antimicrobial resistance (AMR) has developed as one of the major urgent threats to public
health causing serious issues to successful prevention and treatment of persistent diseases …

CAMPR4: a database of natural and synthetic antimicrobial peptides

U Gawde, S Chakraborty, FH Waghu… - Nucleic Acids …, 2023 - academic.oup.com
There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …

The microbial coinfection in COVID-19

X Chen, B Liao, L Cheng, X Peng, X Xu, Y Li… - Applied microbiology …, 2020 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel β-coronavirus,
is the main pathogenic agent of the rapidly spreading pneumonia called coronavirus …