Diabetic nephropathy is one of the most common complications in diabetes. It has been
shown to be the leading cause of end-stage renal disease. However, due to their complex …

Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline
alkaloids. It is found in such plants as Berberis [eg Berberis aquifolium (Oregon grape) …

Oxidative stress and inflammation are proved to be critical for the pathogenesis of diabetes
mellitus. Berberine (BBR) is a natural compound isolated from plants such as Coptis …

A substantial knowledge on the pathogenesis of diabetes mellitus (DM) by oxidative stress
and inflammation is available. Berberine is a biologically active botanical that can combat …

An increasing number of studies suggest that the renal proximal tubule is a site of injury in
diabetic nephropathy (DN), and progressive renal tubulointerstitial fibrosis is an important …

Diabetic Nephropathy (DN) is believed to be a major microvascular complication of
diabetes. The hallmark of DN includes deposition of Extracellular Matrix (ECM) proteins …

Diabetic nephropathy (DN) is a serious kidney-related complication of both type 1 and type 2
diabetes mellitus (T1DM, T2DM) and the second major cause of end-stage kidney disease …

Diabetic kidney disease (DKD) is not only one of the main complications of diabetes, but
also the leading cause of the end-stage renal disease (ESRD). The occurrence and …

Despite improvements in glycaemic and blood pressure control, and the efficacy of renin–
angiotensin system (RAS) blockade for proteinuria reduction, diabetic nephropathy is the …

糖尿病肾病是糖尿病的并发症之一, 在其发病过程中都伴随着复杂的机体代谢紊乱性改变,
目前糖尿病肾病肾损伤的确切发病机制尚未完全明确. 本文综述了潜在的糖尿病肾病治疗靶点 …