The current SARS-CoV-2 pandemic era launched an immediate and broad response of the
research community with studies both about the virus and host genetics. Research in …

Supporting allogeneic hematopoietic cell transplantation (HCT) is an integral function of the
clinical HLA laboratory, which provides HLA testing for recipients and donors. However, the …

The COVID-19 pandemic has serious implications also for patients with other diseases.
Here, we describe the effects of the pandemic on unrelated hematopoietic stem cell …

Abstract Background The SARS‐CoV‐2 pandemic has strained health systems worldwide,
and infection numbers continue to rise. While previous data have already shown that many …

HLA molecules are key restrictive elements to present intracellular antigens at the
crossroads of an effective T-cell response against SARS-CoV-2. To determine the impact of …

Background Bone marrow (BM) transplantation is a life-saving therapy for hematological
diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell …

Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity
mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of …

Introduction Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed
worldwide to treat blood cancer and other life-threatening blood disorders. As successful …

We developed a cost-efficient workflow for genotyping HLA-E by NGS and applied it for
genotyping more than 2.5 million potential stem cell donors. The data obtained were used to …

DKMS is a leading stem cell donor registry with more than 9 million donors. Donor registry
activities share many touch points with topics from immunogenetics or population genetics …