The dark sides of the GPCR tree‐research progress on understudied GPCRs

MM Scharf, LJ Humphrys, S Berndt… - British Journal of …, 2024 - Wiley Online Library
A large portion of the human GPCRome is still in the dark and understudied, consisting even
of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion …

Role of Ectopic Olfactory Receptors in the Regulation of the Cardiovascular–Kidney–Metabolic Axis

MR Beito, S Ashraf, D Odogwu, R Harmancey - Life, 2024 - mdpi.com
Olfactory receptors (ORs) represent one of the largest yet least investigated families of G
protein-coupled receptors in mammals. While initially believed to be functionally restricted to …