Diabetes mellitus has profound effects on multiple organ systems; however, the loss of
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …

Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

The vascular network delivers oxygen (O2) and nutrients to all cells within the body. It is
therefore not surprising that O2 availability serves as a primary regulator of this complex …

Blood vessels constitute the first organ in the embryo and form the largest network in our
body but, sadly, are also often deadly. When dysregulated, the formation of new blood …

The retina resides in an environment that is primed for the generation of reactive oxygen
species (ROS) and resultant oxidative damage. The retina is one of the highest oxygen …

Background Cardiovascular risk factors contribute to atherogenesis by inducing endothelial-
cell injury and dysfunction. We hypothesized that endothelial progenitor cells derived from …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

Retinal and choroidal vascular diseases constitute the most common causes of moderate
and severe vision loss in developed countries. They can be divided into retinal vascular …

Background—The recent discovery of circulating endothelial progenitor cells (EPCs) has
altered our understanding of new blood vessel growth such as occurs during collateral …