The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Fecal indicator bacteria from environmental sources; strategies for identification to improve water quality monitoring

ML Devane, E Moriarty, L Weaver, A Cookson, B Gilpin - Water Research, 2020 - Elsevier
In tropical to temperate environments, fecal indicator bacteria (FIB), such as enterococci and
Escherichia coli, can persist and potentially multiply, far removed from their natural reservoir …

Species-and site-specific genome editing in complex bacterial communities

BE Rubin, S Diamond, BF Cress, A Crits-Christoph… - Nature …, 2022 - nature.com
Understanding microbial gene functions relies on the application of experimental genetics in
cultured microorganisms. However, the vast majority of bacteria and archaea remain …

The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity

Z Zhou, NF Alikhan, K Mohamed, Y Fan… - Genome …, 2020 - genome.cshlp.org
EnteroBase is an integrated software environment that supports the identification of global
population structures within several bacterial genera that include pathogens. Here, we …

Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries

K Sands, MJ Carvalho, E Portal, K Thomson… - Nature …, 2021 - nature.com
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of resistance that often
spread between species via mobile genetic elements, ultimately limiting treatments in low …

In Silico Genotyping of Escherichia coli Isolates for Extraintestinal Virulence Genes by Use of Whole-Genome Sequencing Data

AM Malberg Tetzschner, JR Johnson… - Journal of clinical …, 2020 - Am Soc Microbiol
ABSTRACT Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause in
humans of urinary tract infection and bacteremia. The previously published web tool …

Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice

YE Gencay, D Jasinskytė, C Robert, S Semsey… - Nature …, 2024 - nature.com
Antibiotic treatments have detrimental effects on the microbiome and lead to antibiotic
resistance. To develop a phage therapy against a diverse range of clinically relevant …

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

M Touchon, A Perrin, JAM De Sousa, B Vangchhia… - PLoS …, 2020 - journals.plos.org
Escherichia coli is mostly a commensal of birds and mammals, including humans, where it
can act as an opportunistic pathogen. It is also found in water and sediments. We …

Characterization and rapid identification of phylogroup G in Escherichia coli, a lineage with high virulence and antibiotic resistance potential

O Clermont, OVA Dixit, B Vangchhia… - Environmental …, 2019 - Wiley Online Library
The phylogeny of the Escherichia coli species, with the identification of seven phylogroups
(A, B1, B2, C, D, E and F), is linked to the lifestyle of the strains. With the accumulation of …

Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape

DM Muloi, BA Wee, DMH McClean, MJ Ward… - Nature …, 2022 - nature.com
Quantitative evidence for the risk of zoonoses and the spread of antimicrobial resistance
remains lacking. Here, as part of the UrbanZoo project, we sampled Escherichia coli from …