A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery
SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …
starts from the genomic sequence of the pathogen and ends with a list of potential protein …
[HTML][HTML] Multi-epitope chimeric vaccine design against emerging Monkeypox virus via reverse vaccinology techniques- a bioinformatics and immunoinformatics …
S Aiman, Y Alhamhoom, F Ali, N Rahman… - Frontiers in …, 2022 - frontiersin.org
The emerging monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes infections in
humans similar to smallpox. Since May 2022, cases of monkeypox (MPX) have been …
humans similar to smallpox. Since May 2022, cases of monkeypox (MPX) have been …
Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens
Vaccines have significantly reduced the impact of numerous deadly viral infections.
However, there is an increasing need to expedite vaccine development in light of the …
However, there is an increasing need to expedite vaccine development in light of the …
Novel multi epitope-based vaccine against monkeypox virus: vaccinomic approach
While mankind is still dealing with the COVID-19 pandemic, a case of monkeypox virus
(MPXV) has been reported to the WHO on May 7, 2022. Monkeypox is a viral zoonotic …
(MPXV) has been reported to the WHO on May 7, 2022. Monkeypox is a viral zoonotic …
Immunoinformatics Aided Design and In-Vivo Validation of a Cross-Reactive Peptide Based Multi-Epitope Vaccine Targeting Multiple Serotypes of Dengue Virus
Dengue virus (DENV) is an arboviral disease affecting more than 400 million people
annually. Only a single vaccine formulation is available commercially and many others are …
annually. Only a single vaccine formulation is available commercially and many others are …
Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach
The current global outbreak of monkeypox (MPX) disease, caused by Monkeypox virus
(MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a …
(MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a …
In silico design and analyses of a multi-epitope vaccine against Crimean-Congo hemorrhagic fever virus through reverse vaccinology and immunoinformatics …
Abstract Crimean Congo Hemorrhagic Fever virus (CCHFV) is a deadly human pathogen
that causes an emerging zoonotic disease with a broad geographic spread, especially in …
that causes an emerging zoonotic disease with a broad geographic spread, especially in …
Immunoinformatics design of multivalent epitope vaccine against monkeypox virus and its variants using membrane-bound, enveloped, and extracellular proteins as …
Introduction The current monkeypox (MPX) outbreak, caused by the monkeypox virus
(MPXV), has turned into a global concern, with over 59,000 infection cases and 23 deaths …
(MPXV), has turned into a global concern, with over 59,000 infection cases and 23 deaths …
[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis
BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
Bioinformatics approach for the construction of multiple epitope vaccine against omicron variant of SARS-CoV-2
Abstract The World Health Organization categorized SARS-CoV-2 as a variant of concern,
having numerous mutations in spike protein, which have been found to evade the effect of …
having numerous mutations in spike protein, which have been found to evade the effect of …