Background Previous research has investigated the efficacy of clozapine in reducing
suicidality in patients with schizophrenia and schizoaffective disorder. We aimed to …

Schizophrenia is a heterogenous and severe neuropsychiatric disorder that affects nearly
1% of the population worldwide. Antipsychotic drugs are the mainstay of treatment, but not …

Objective: This study evaluated rates of all-cause mortality and self-harm in association with
clozapine treatment in individuals with treatment-resistant schizophrenia. Method: A …

Suicide is a public health crisis with limited treatment options. Ketamine has demonstrated
rapid and robust improvements in suicidal ideation (SI). The parent study for the secondary …

Background: clozapine (CLZ) use is precarious due to its neurological, cardiovascular, and
hematological side effects; however, it is the gold standard in therapy-resistant …

After the introduction of clozapine eight Finnish patients died after developing
agranulocytosis. Clozapine was withdrawn from the market and only reintroduced with strict …

Aim Clozapine is indicated as the last-line agent for the treatment of refractory schizophrenia
due to its side effects. This study included an Asian schizophrenia population and …

Objective To compare the mortality in people using clozapine to that of people using other
antipsychotics. Methods Danish incidence cohort of 22,110 patients with a first diagnosis of …

Popular media often portray people with a mental illness as being aggressive, violent, and
incarcerated as a result of their behavior. Despite exaggeration in the media, risks for some …

Although clozapine is more effective than other antipsychotics in the treatment of
schizophrenia, the rate of its discontinuation is also high. The aim of this retrospective chart …