The transport of fluid in and around nanometer-sized objects with at least one characteristic
dimension below 100 nm enables the occurrence of phenomena that are impossible at …

Common strategies employed for general protein detection include organic dye, silver stain,
radiolabeling, reverse stain, fluorescent stain, chemiluminescent stain and mass …

A new technique is described for the concentration and separation of ionic species in
solution within microchannels or capillaries. Concentration is achieved by balancing the …

A previously undescribed isoelectric focusing technology allows cell signaling to be
quantitatively assessed in< 25 cells. High-resolution capillary isoelectric focusing allows …

We have developed an acrylic microfluidic device that sequentially couples liquid-phase
isoelectric focusing (IEF) and free solution capillary electrophoresis (CE). Rapid separation …

Compacted DNA nanoparticles deliver transgenes efficiently to the lung following
intrapulmonary dosing. Here we show that nucleolin, a protein known to shuttle between the …

Methods are described to achieve more efficient multidimensional protein separation in a
microfluidic channel. The new methods couple isoelectric focusing (IEF) with high ionic …

Cytometry deals with the analysis of the composition of single cells. Flow and image
cytometry employ antibody-based stains to characterize a handful of components in single …

Amorphous silicon-based ion-sensitive field-effect transistors (a-Si: H ISFETs) are used for
the label-free detection of biological molecules. The covalent immobilization of DNA …

This survey gives an overview of recent derivatization protocols, starting from 1996, in
combination with capillary electrophoresis (CE). Derivatization is mainly used for enhancing …