[HTML][HTML] The molecular basis of antimalarial drug resistance in Plasmodium vivax

LE Buyon, B Elsworth, MT Duraisingh - International Journal for …, 2021 - Elsevier
Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

Plasmodium genomics: an approach for learning about and ending human malaria

JA Garrido-Cardenas, L González-Cerón… - Parasitology …, 2019 - Springer
Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …

Antimalarial drug resistance: A brief history of its spread in Indonesia

LE Fitri, AR Pawestri, N Winaris… - Drug Design …, 2023 - Taylor & Francis
Malaria remains to be a national and global challenge and priority, as stated in the strategic
plan of the Indonesian Ministry of Health and Sustainable Development Goals. In Indonesia …

Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia

FV Rahmasari, PBS Asih, FK Dewayanti… - Malaria Journal, 2022 - Springer
This review article aims to investigate the genotypic profiles of Plasmodium falciparum and
Plasmodium vivax isolates collected across a wide geographic region and their association …

Drug resistance markers in Plasmodium vivax isolates from a Kanchanaburi province, Thailand between January to May 2023

T Sridapan, P Rattanakoch, K Kijprasong, S Srisutham - Plos one, 2024 - journals.plos.org
Background Plasmodium vivax has become the predominant species in the border regions
of Thailand. The emergence and spread of antimalarial drug resistance in P. vivax is one of …

Polymorphisms of potential drug resistant molecular markers in Plasmodium vivax from China–Myanmar border during 2008‒2017

Z Wang, C Wei, Y Pan, Z Wang, X Ji, Q Chen… - Infectious Diseases of …, 2022 - Springer
Background Plasmodium vivax remains the predominant species at the China–Myanmar
border, imposing a major challenge to the recent gains in regional malaria elimination. To …

Overlap extension barcoding for the next generation sequencing and genotyping of Plasmodium falciparum in individual patients in Western Kenya

B Levitt, A Obala, S Langdon, D Corcoran… - Scientific reports, 2017 - nature.com
Large-scale molecular epidemiologic studies of Plasmodium falciparum parasites have
provided insights into parasite biology and transmission, can identify the spread of drug …

Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia

N Saralamba, S Nakeesathit, M Mayxay, PN Newton… - Malaria Journal, 2016 - Springer
Background Non-synonymous mutations in dhfr and dhps genes in Plasmodium vivax are
associated with sulfadoxine–pyrimethamine (SP) resistance. The present study aimed to …

Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia

S Basuki, Fitriah, PM Risamasu, Kasmijati, P Ariami… - Malaria Journal, 2018 - Springer
Background While malaria incidence in Indonesia has decreased threefold in the last
decade, more than 200,000 cases were reported in 2016. Different endemicity of …

Molecular Detection of Antimalarial Drug Resistance in Plasmodium vivax from Returned Travellers to NSW, Australia during 2008–2018

C Noisang, W Meyer, N Sawangjaroen, J Ellis, R Lee - Pathogens, 2020 - mdpi.com
To monitor drug resistance in Plasmodium vivax, a multidrug resistance 1 (Pvmdr1) gene
and a putative transporter protein (Pvcrt-o) gene were used as molecular markers for …