Molecular tumour boards—current and future considerations for precision oncology

AM Tsimberidou, M Kahle, HH Vo, MA Baysal… - Nature Reviews …, 2023 - nature.com
Over the past 15 years, rapid progress has been made in developmental therapeutics,
especially regarding the use of matched targeted therapies against specific oncogenic …

A clinician's handbook for using ctDNA throughout the patient journey

SO Hasenleithner, MR Speicher - Molecular cancer, 2022 - Springer
Background The promise of precision cancer medicine presently centers around the
genomic sequence of a patient's tumor being translated into timely, actionable information to …

Circulating tumor DNA: current challenges for clinical utility

DK Dang, BH Park - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
Cancer cells shed naked DNA molecules into the circulation. This circulating tumor DNA
(ctDNA) has become the predominant analyte for liquid biopsies to understand the …

Barriers and facilitators to next-generation sequencing use in United States oncology settings: a systematic review

A Ferreira-Gonzalez, G Ko, N Fusco, F Stewart… - Future …, 2024 - Taylor & Francis
Aim: Next-generation sequencing (NGS) of solid tumors can inform treatment decisions;
however, uptake remains low. This objective of this systematic review was to identify barriers …

The report says what?: how the medical microbiologist can aid in the interpretation of next-generation sequencing results

C Costales, JD Bard - Clinics in Laboratory Medicine, 2024 - labmed.theclinics.com
As precision medicine evolves and access to complex infectious molecular testing in the
clinical environment continues to become more widely available, the medical microbiologist …

MTPpilot: an interactive software for visualization of next-generation sequencing results in molecular tumor boards

A Kahraman, FM Arnold, J Hanimann… - JCO Clinical Cancer …, 2022 - ascopubs.org
PURPOSE Comprehensive targeted next-generation sequencing (NGS) panels are
routinely used in modern molecular cancer diagnostics. In molecular tumor boards, the …

[HTML][HTML] Molecular Tumor Board of the University Medical Center Groningen (UMCG-MTB): outcome of patients with rare or complex mutational profiles receiving MTB …

VD de Jager, P Plomp, MS Paats, S van Helvert… - ESMO open, 2024 - Elsevier
Purpose Molecular tumor boards (MTBs) are considered beneficial for treatment decision
making for patients with cancer with uncommon, rare, or complex mutational profiles. The …

The Minimal Dataset for Cancer of the 1+ Million Genomes Initiative

M Riba, C Sala, A Culhane, Å Flobak, A Patocs, K Boye… - bioRxiv, 2023 - biorxiv.org
For a real impact on healthcare, precision cancer medicine requires accessibility and
interoperability of clinical and genomic data across centres and countries. Due to the …

Quality Measures for Multidisciplinary Tumor Boards and Their Role in Improving Cancer Care

KA Abuelgasim, AR Jazieh - Global Journal on Quality and …, 2024 - meridian.allenpress.com
While multidisciplinary tumor boards (MTBs) are widely used in managing patients with
cancer, their impact on patient care and outcome is not routinely measured in different …

Molecular tumor board and theranostics

PO Rumyantsev - Problemy Endokrinologii, 2023 - europepmc.org
Клиническая онкология сегодня проходит период беспрецедентных изменений.
Таргетная терапия, а в последующем иммунотерапия, революционизировали …