The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that
interacts with photoreceptors on its apical side and with Bruch's membrane and the …

The complement system is an essential element of the innate immune response that
becomes activated upon recognition of molecular patterns associated with microorganisms …

The present invention relates to an immunogenic composi tion. More particularly, the
present invention is a composition directed to eliciting an immune response to at least one …

The factor H (FH) protein family is emerging as a complex network of proteins controlling the
fate of the complement alternative pathway (AP) and dictating susceptibility to a wide range …

The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …

Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the
complement system in plasma and in the protection of bystander host cells and tissues from …

C-reactive protein (CRP) is an acute-phase serum protein and a mediator of innate
immunity. CRP binds to microbial polysaccharides and to ligands exposed on damaged …

Factor H (fH), a key alternative complement pathway regulator, is a cofactor for factor I–
mediated cleavage of C3b. fH consists of 20 short consensus repeat (SCR) domains. Sialic …

The complement system consists of about 35–40 proteins and glycoproteins present in
blood plasma or on cell surfaces. Its main biological function is to recognise “foreign” …

Summary OTHER ARTICLES PUBLISHED IN THIS TRANSLATIONAL MINI-REVIEW
SERIES ON COMPLEMENT FACTOR H Structural and functional correlations for factor H …