The frontotemporal dementia-motor neuron disease continuum

JR Burrell, GM Halliday, JJ Kril, LM Ittner, J Götz… - The Lancet, 2016 - thelancet.com
Early reports of cognitive and behavioural deficits in motor neuron disease might have been
overlooked initially, but the concept of a frontotemporal dementia-motor neuron disease …

Progress and challenges in frontotemporal dementia research: a 20-year review

JR Hodges, O Piguet - Journal of Alzheimer's disease, 2018 - content.iospress.com
The landscape of frontotemporal dementia (FTD) has evolved remarkably in recent years
and is barely recognizable from two decades ago. Knowledge of the clinical …

Longitudinal multimodal MRI as prognostic and diagnostic biomarker in presymptomatic familial frontotemporal dementia

LC Jiskoot, JL Panman, LH Meeter, EGP Dopper… - Brain, 2019 - academic.oup.com
Developing and validating sensitive biomarkers for the presymptomatic stage of familial
frontotemporal dementia is an important step in early diagnosis and for the design of future …

Presymptomatic spinal cord pathology in c9orf72 mutation carriers: A longitudinal neuroimaging study

G Querin, P Bede, MM El Mendili, M Li… - Annals of …, 2019 - Wiley Online Library
Objective C9orf72 hexanucleotide repeats expansions account for almost half of familial
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) cases. Recent …

Motor neuron disease-frontotemporal dementia: a clinical continuum

E Devenney, S Vucic, JR Hodges… - Expert review of …, 2015 - Taylor & Francis
Overlap between motor neuron disease (MND) and frontotemporal dementia (FTD) occurs at
clinical, genetic and pathological levels, and has been recently strengthened through the …

Progression in behavioral variant frontotemporal dementia: a longitudinal study

E Devenney, L Bartley, C Hoon, C O'Callaghan… - JAMA …, 2015 - jamanetwork.com
Importance A gap in the literature exists regarding progression in behavioral variant
frontotemporal dementia (BVFTD). Guidance is needed concerning markers that will enable …

[HTML][HTML] Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

S Häkkinen, SA Chu, SE Lee - Neurobiology of disease, 2020 - Elsevier
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) have a strong
clinical, genetic and pathological overlap. This review focuses on the current understanding …

Frontotemporal dementia

EM Devenney, RM Ahmed, JR Hodges - Handbook of clinical neurology, 2019 - Elsevier
Frontotemporal dementia (FTD) is the second commonest cause of young onset dementia.
Our understanding of FTD and its related syndromes has advanced significantly in recent …

Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis

JM Gregory, K McDade, MR Livesey… - Neuropathology and …, 2020 - Wiley Online Library
Aims The mechanisms underlying the selective degeneration of motor neurones in
amyotrophic lateral sclerosis (ALS) are poorly understood. The aim of this study was to …

Frontotemporal dementia and late-onset bipolar disorder: the many directions of a busy road

MN Maia da Silva, FHG Porto, PMG Lopes… - Frontiers in …, 2021 - frontiersin.org
It is a common pathway for patients with the behavioral variant of frontotemporal dementia
(bvFTD) to be first misdiagnosed with a primary psychiatric disorder, a considerable …