piRNAs and PIWI proteins: regulators of gene expression in development and stem cells

P Rojas-Ríos, M Simonelig - Development, 2018 - journals.biologists.com
ABSTRACT PIWI proteins and Piwi-interacting RNAs (piRNAs) have established and
conserved roles in repressing transposable elements (TEs) in the germline of animals …

[HTML][HTML] It's just a phase: exploring the relationship between mRNA, biomolecular condensates, and translational control

DM Parker, LP Winkenbach… - Frontiers in …, 2022 - frontiersin.org
Cells spatially organize their molecular components to carry out fundamental biological
processes and guide proper development. The spatial organization of RNA within the cell …

The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes

D Zhang, S Tu, M Stubna, WS Wu, WC Huang, Z Weng… - Science, 2018 - science.org
Piwi-interacting RNAs (piRNAs) silence transposons to safeguard genome integrity in
animals. However, the functions of the many piRNAs that do not map to transposons remain …

A single mechanism of biogenesis, initiated and directed by PIWI proteins, explains piRNA production in most animals

I Gainetdinov, C Colpan, A Arif, K Cecchini, PD Zamore - Molecular cell, 2018 - cell.com
In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and
regulate gene expression. The mechanisms for making piRNAs have been proposed to …

A review of discovery profiling of PIWI-interacting RNAs and their diverse functions in metazoans

S Huang, K Yoshitake, S Asakawa - International Journal of Molecular …, 2021 - mdpi.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs (sncRNAs) that
perform crucial biological functions in metazoans and defend against transposable elements …

pirScan: a webserver to predict piRNA targeting sites and to avoid transgene silencing in C. elegans

WS Wu, WC Huang, JS Brown, D Zhang… - Nucleic acids …, 2018 - academic.oup.com
Abstract pirScan is a web-based tool for identifying C. elegans piRNA-targeting sites within a
given mRNA or spliced DNA sequence. The purpose of our tool is to allow C. elegans …

Spermatozoa expression of piR-31704, piR-39888, and piR-40349 and their correlation to sperm concentration and fertilization rate after ICSI

L Cui, L Fang, B Shi, S Qiu, Y Ye - Reproductive Sciences, 2018 - journals.sagepub.com
Objective: To investigate the relationship between spermatozoa PIWI-interacting RNAs
(piRNAs) levels and semen parameters and to evaluate the role of expression of piRNAs on …

Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells

AA Ilyin, SS Ryazansky, SA Doronin… - Nucleic acids …, 2017 - academic.oup.com
Piwi in a complex with Piwi-interacting RNAs (piRNAs) triggers transcriptional silencing of
transposable elements (TEs) in Drosophila ovaries, thus ensuring genome stability. To do …

Insights in piRNA targeting rules

JC van Wolfswinkel - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) play an important role in the defense against transposons
in the germline and stem cells of animals. To what extent other transcripts are also regulated …

Activation of DNA Transposons and Evolution of piRNA Genes Through Interspecific Hybridization in Xenopus Frogs

K Suda, SR Hayashi, K Tamura, N Takamatsu… - Frontiers in …, 2022 - frontiersin.org
Interspecific hybridization between two closely related species sometimes resulted in a new
species with allotetraploid genomes. Many clawed frog species belonging to the Xenopus …