Cellular signalling by primary cilia in development, organ function and disease

Z Anvarian, K Mykytyn, S Mukhopadhyay… - Nature Reviews …, 2019 - nature.com
Primary cilia project in a single copy from the surface of most vertebrate cell types; they
detect and transmit extracellular cues to regulate diverse cellular processes during …

Primary cilium-dependent signaling mechanisms

R Pala, N Alomari, SM Nauli - International journal of molecular sciences, 2017 - mdpi.com
Primary cilia are hair-like organelles and play crucial roles in vertebrate development,
organogenesis, health, and many genetic disorders. A primary cilium is a mechano-sensory …

[HTML][HTML] Agronomy, nutritional value, and medicinal application of faba bean (Vicia faba L.)

F Etemadi, M Hashemi, AV Barker, OR Zandvakili… - Horticultural Plant …, 2019 - Elsevier
Faba bean (Vicia faba L.) is a cool season grain legume crop with the potential to be grown
as multi-purpose crop in areas with short growing season. Faba bean is grown in many …

Ins and outs of GPCR signaling in primary cilia

KB Schou, LB Pedersen, ST Christensen - EMBO reports, 2015 - embopress.org
Primary cilia are specialized microtubule‐based signaling organelles that convey
extracellular signals into a cellular response in most vertebrate cell types. The physiological …

Intraflagellar transport proteins as regulators of primary cilia length

W Wang, BM Jack, HH Wang… - Frontiers in cell and …, 2021 - frontiersin.org
Primary cilia are small, antenna-like organelles that detect and transduce chemical and
mechanical cues in the extracellular environment, regulating cell behavior and, in turn …

Insights into the circadian rhythm alterations of the novel PFOS substitutes F-53B and OBS on adult zebrafish

Q Wang, X Gu, Y Liu, S Liu, W Lu, Y Wu, H Lu… - Journal of Hazardous …, 2023 - Elsevier
As alternatives to perfluorooctane sulfonate (PFOS), 6: 2 Cl-PFESA (F-53B) and sodium p-
perfluorous nonenoxybenzene sulfonate (OBS) are frequently detected in aquatic …

[HTML][HTML] Signal transduction in primary cilia–analyzing and manipulating GPCR and second messenger signaling

D Wachten, DU Mick - Pharmacology & therapeutics, 2021 - Elsevier
The primary cilium projects from the surface of most vertebrate cells, where it senses
extracellular signals to regulate diverse cellular processes during tissue development and …

G-protein-coupled receptor signaling in cilia

K Mykytyn, C Askwith - Cold Spring Harbor perspectives …, 2017 - cshperspectives.cshlp.org
G-protein-coupled receptors (GPCRs) are the largest and most versatile family of signaling
receptors in humans. They respond to diverse external signals, such as photons, proteins …

[HTML][HTML] Lengthening primary cilia enhances cellular mechanosensitivity

M Spasic, CR Jacobs - European cells & materials, 2017 - ncbi.nlm.nih.gov
The primary cilium is a mechanosensor in a variety of mammalian cell types, initiating and
directing intracellular signaling cascades in response to external stimuli. When primary cilia …

Osteocytes and Primary Cilia

SW Verbruggen, A Sittichokechaiwut… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to provide a background on
osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing …