Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …

Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …

New neurons continue to be generated in the subgranular zone of the dentate gyrus of the
adult mammalian hippocampus,,,,. This process has been linked to learning and memory …

A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

The Notch pathway is often regarded as a developmental pathway, but components of Notch
signalling are expressed and active in the adult brain. With the advent of more sophisticated …

The mammalian retina displays no intrinsic regenerative capacities, therefore retinal
degenerative diseases such as age-related macular degeneration (AMD) or retinitis …

Microglia cells are the major orchestrator of the brain inflammatory response. As such, they
are traditionally studied in various contexts of trauma, injury, and disease, where they are …

Proliferating neural stem cells and intermediate progenitors persist in the ventricular-
subventricular zone (V-SVZ) of the adult mammalian brain. This extensive germinal layer in …

Stem cells are captivating because they have the potential to make multiple cell types yet
maintain their undifferentiated state. Recent studies of Drosophila and mammalian neural …

Spinal cord injury typically results in permanent disability. Many studies have indicated that
transplantation of several different types of stem cells promotes functional recovery in animal …