Rapid advancements in the area of early cancer detection have brought us closer to
achieving the goals of finding cancer early enough to treat or cure it, while avoiding harms of …

The innate immune system is the first line of defense against invading pathogens or sterile
injuries. Pattern recognition receptors (PRR) sense molecules released from inflamed or …

Excessive cell-free DNA (cfDNA) released by damaged or apoptotic cells can cause
inflammation, impacting the progression of rheumatoid arthritis (RA). cfDNA scavengers …

Endogenous DNA derived from the nuclei or mitochondria is released into the bloodstream
following cell damage or death. Extracellular DNA, called cell-free DNA (cfDNA), is …

Simple Summary DNA release from tumour cells (call circulating tumour DNA) into the blood
stream can be found in patients with gastric cancer through a blood test call a liquid biopsy …

Macromolecular Toll-like receptor (TLR) agents have been utilized as agonists and
inhibitors in preclinical and clinical settings. These agents interface with the TLR class of …

Abstract Purpose Primary Sjögren's syndrome (pSS) is an autoimmune disease that mainly
attacks the lacrimal glands causing severe aqueous-deficient dry eye. Clinical evidence …

Increased levels of circulating cell‐free DNA (cfDNA) are associated with poor clinical
outcomes in patients with acute kidney injury (AKI). Scavenging cfDNA by nanomaterials is …

Simple Summary Early diagnosis of renal cell carcinoma (RCC) is challenging and typically
incidental. Currently, several therapeutic strategies are used for the treatment; however, no …

Atherosclerosis (AS) is the leading cause of cardiovascular diseases (CVDs) with a high rate
of mortality worldwide. Plasma cell-free DNA (cfDNA), mainly originating from apoptosis …