Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
Antioxidant and antimicrobial peptides derived from food proteins
G López-García, O Dublan-García, D Arizmendi-Cotero… - Molecules, 2022 - mdpi.com
Recently, the demand for food proteins in the market has increased due to a rise in
degenerative illnesses that are associated with the excessive production of free radicals and …
degenerative illnesses that are associated with the excessive production of free radicals and …
Peptides with dual antimicrobial and anticancer activities
In recent years, the number of people suffering from cancer and multi-resistant infections has
increased, such that both diseases are already seen as current and future major causes of …
increased, such that both diseases are already seen as current and future major causes of …
How membrane-active peptides get into lipid membranes
MA Sani, F Separovic - Accounts of chemical research, 2016 - ACS Publications
Conspectus The structure–function relationship for a family of antimicrobial peptides (AMPs)
from the skin of Australian tree frogs is discussed and compared with that of peptide toxins …
from the skin of Australian tree frogs is discussed and compared with that of peptide toxins …
Antimicrobial peptides: challenging journey to the pharmaceutical, biomedical, and cosmeceutical use
A Mazurkiewicz-Pisarek, J Baran, T Ciach - International journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
The chemistry and biological activities of peptides from amphibian skin secretions
X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …
environmental factors including microorganisms, parasites, predators, and physical factors …
Recurrent neural network model for constructive peptide design
We present a generative long short-term memory (LSTM) recurrent neural network (RNN) for
combinatorial de novo peptide design. RNN models capture patterns in sequential data and …
combinatorial de novo peptide design. RNN models capture patterns in sequential data and …
[HTML][HTML] Studies on anticancer activities of antimicrobial peptides
DW Hoskin, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …
developing anticancer agents with a new mode of action because of the development of …
[HTML][HTML] Membrane-active host defense peptides–challenges and perspectives for the development of novel anticancer drugs
S Riedl, D Zweytick, K Lohner - Chemistry and physics of lipids, 2011 - Elsevier
Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …
recent decades, problems continue to arise particularly with respect to chemotherapy due to …