Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …

Gut bacteria are linked to neurodegenerative diseases but the risk factors beyond microbiota
composition are limited. Here we used a pre-clinical model of multiple sclerosis (MS) …

Pathobionts employ unique metabolic adaptation mechanisms to maximize their growth in
disease conditions. Adherent-invasive Escherichia coli (AIEC), a pathobiont enriched in the …

The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in
heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium …

In early life, the intestinal mucosa and immune system undergo a critical developmental
process to contain the expanding gut microbiome while promoting tolerance toward …

The capacity of the intestinal microbiota to degrade otherwise indigestible diet components
is known to greatly improve the recovery of energy from food. This has led to the hypothesis …

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the
gastrointestinal tract. The etiology of IBD remains elusive, but the disease is suggested to …

Cytotoxic chemotherapies have devastating side effects, particularly within the
gastrointestinal tract. Gastrointestinal toxicity includes the death and damage of the …

Persons with cystic fibrosis (CF), starting in early life, show intestinal microbiome dysbiosis
characterized in part by a decreased relative abundance of the genus Bacteroides …

Background Dietary fibers can alter microbial metabolic output in support of healthy immune
function; however, the impact of distinct fiber sources and immunomodulatory effects beyond …