Resistance to antibiotics is a major global problem and there is an urgent need to develop
new therapeutic agents. Although many classes of active compounds have been …

In the last few decades, a lot of work has been done on heterocycles, especially the
imidazole ring, to obtain a scaffold with potential pharmacological properties such as …

A series of 2′-hydroxy-chalcones and their oxidative cyclization products, aurones, have
been synthesized and tested for their antioxidant and lipoxygenase inhibitory activity. The …

The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …

The first review regarding the potential of aurones as promising drug candidates was
reported in 2003. Since, considerable efforts have been made to explore the …

Parasitic and bacterial infections affecting the gastrointestinal tract represent a significant
cause of morbidity and mortality worldwide. Nitroheterocyclic drugs have been available …

A set of variously substituted aurones was synthesized and evaluated against Methicillin-
Resistant S. aureus (MRSA) and P. aeruginosa. Several analogues were found active …

This is the first report on aurones as a new class of drugs with anti-inflammatory and
antimicrobial agents. A series of 2, 2-bisaminomethylated aurone analogues (4a–j) were …

Hybrid molecules have become a well-established and powerful biologically relevant
heterocycles. They constitute a core structure due to their widespread use in pharmaceutical …

Two series of ten chalcones and ten aurones, where ferrocene replaces the C ring and with
diverse substituents on the A ring were synthesized. The compounds were tested against …