Tissue regeneration has been in the spotlight of research for its fascinating nature and
potential applications in human diseases. The trait of regenerative capacity occurs diversely …

Ability of environmental stressors to induce transgenerational diseases has been
experimentally demonstrated in plants, worms, fish, and mammals, indicating that exposures …

Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

Centromeres and large-scale structural variants evolve and contribute to genome diversity
during vertebrate speciation. Here, we perform de novo long-read genome assembly of …

Epigenetic mechanisms such as DNA methylation are a key component of dosage
compensation on sex chromosomes and have been proposed as an important source of …

DNA methylation is a critical epigenetic regulator of development in mammals and social
insects, but its significance in development outside these groups is not understood. Here we …

Individual recognition (IR) is essential for maintaining various social interactions in a group,
and face recognition is one of the most specialised cognitive abilities in IR. We used both a …

Chromatin looping plays an important role in genome regulation. However, because ChIP-
seq and loop-resolution Hi-C (DNA-DNA proximity ligation) are extremely challenging in …

DNA methylation is a dynamic epigenetic modification with an important role in cell fate
specification and reprogramming. The Ten eleven translocation (Tet) family of enzymes …

Determining genes that orchestrate cell differentiation in development and disease remains
a fundamental goal of cell biology. This study establishes a genome-wide metric based on …