[HTML][HTML] Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity

S Mitra, AJ Chakraborty, AM Tareq, TB Emran… - Journal of King Saud …, 2022 - Elsevier
Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in
the atmosphere, and ability to accumulate in the human body via bioaccumulation. The …

Cr (VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway

SC Fu, JM Liu, KI Lee, FC Tang, KM Fang, CY Yang… - Toxicology in Vitro, 2020 - Elsevier
Abstract Hexavalent chromium (Cr (VI)), a well-known toxic industrial and environmental
pollutant, has been shown to cause serious toxic and health effects. However, limited …

Rosmarinus officinalis essential oil modulates renal toxicity and oxidative stress induced by potassium dichromate in rats

FM El-Demerdash, RA El-Sayed… - Journal of Trace Elements …, 2021 - Elsevier
BACKGROUND Chromium hexavalent (CrVI) is known as a toxic contaminant that induced
oxidative stress and nephrotoxicity in humans and animals. Rosmarinus officinalis is a …

Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats

A Fedala, O Adjroud, S Abid-Essefi… - Environmental Science and …, 2021 - Springer
Hexavalent chromium (CrVI) is an environmental pollutant and an endocrine-disrupting
metal. Se and Zn are essential trace elements, known to play a crucial role in thyroid …

Ameliorative effect of aqueous avocado seed extract against chromium‐induced oxidative stress and cellular damage in rabbit kidney

HA Okail, S Anjum, NM Emam… - Food Science & …, 2024 - Wiley Online Library
The accumulation of chromium in renal tissues promotes the generation of reactive oxygen
species (ROS), leading to oxidative stress, genomic and cellular harm, and ultimately …

[HTML][HTML] Bone marrow mesenchymal stem cells repair Cr (VI)-injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK …

F Yin, J Yan, Y Zhao, KJ Guo, ZL Zhang, AP Li… - Ecotoxicology and …, 2019 - Elsevier
The present study aimed to explore the repair effect and mechanism of bone marrow
mesenchymal stem cells (BMSCs) transplantation on injured kidneys caused by hexavalent …

An Overview of Hexavalent Chromium-Induced Necroptosis, Pyroptosis, and Ferroptosis

S Kurmangaliyeva, K Baktikulova, V Tkachenko… - … Trace Element Research, 2024 - Springer
Heavy metals are common environmental industrial pollutants. Due to anthropogenic
activity, chromium, especially its hexavalent form [Cr (VI)], is a widespread environmental …

Atorvastatin prevents cadmium-induced renal toxicity in a rat model

E Karami, Z Goodarzi, A Ghanbari… - Toxicology and …, 2023 - journals.sagepub.com
In many industrial processes, worker exposure to cadmium causes kidney damage; thus,
protection against cadmium toxicity is important in workplace health. Cadmium toxicity …

An evaluation of hepatotoxicity, nephrotoxicity, and genotoxicity induced by acute toxicity of hexavalent chromium and comparison of the possible protective role of …

M Hassan, W Abd-Elwahab, R Megahed… - Ain Shams Journal of …, 2019 - journals.ekb.eg
Introduction Hexavalent chromium Cr (VI) is a strong oxidizing toxic agent. It penetrates cell
membrane and quickly reduced with production of reactive intermediates and reactive …

Nephroprotective Efficacy of Selenium and Zinc Against Potassium Dichromate-Induced Renal Toxicity in Pregnant Wistar Albino Rats

A Fedala, O Adjroud, O Bennoune… - … Trace Element Research, 2022 - Springer
Hexavalent chromium (CrVI) compounds are potent toxicants commonly used in numerous
industries. Thus, potential toxic effects and health hazards are of high relevance. Selenium …