[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system

TCA Hitch, LJ Hall, SK Walsh, GE Leventhal, E Slack… - Mucosal …, 2022 - Elsevier
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

Role of the microbiota in response to and recovery from cancer therapy

SJ Blake, Y Wolf, B Boursi, DJ Lynn - Nature Reviews Immunology, 2024 - nature.com
Our understanding of how the microbiota affects the balance between response to and
failure of cancer treatment by modulating the tumour microenvironment and systemic …

Drivers and determinants of strain dynamics following fecal microbiota transplantation

TSB Schmidt, SS Li, OM Maistrenko, W Akanni… - Nature medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is a therapeutic intervention for inflammatory
diseases of the gastrointestinal tract, but its clinical mode of action and subsequent …

Transferable immunoglobulin A–Coated Odoribacter splanchnicus in responders to fecal microbiota transplantation for ulcerative colitis limits colonic inflammation

SF Lima, L Gogokhia, M Viladomiu, L Chou, G Putzel… - Gastroenterology, 2022 - Elsevier
Background & Aims Fecal microbiota transplantation (FMT) is an emerging treatment
modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy …

Gut bacterial characteristics of patients with type 2 diabetes mellitus and the application potential

Y Que, M Cao, J He, Q Zhang, Q Chen, C Yan… - Frontiers in …, 2021 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a complex disorder comprehensively influenced by
genetic and environmental risk, and research increasingly has indicated the role of microbial …

Recipient-independent, high-accuracy FMT-response prediction and optimization in mice and humans

O Shtossel, S Turjeman, A Riumin, MR Goldberg… - Microbiome, 2023 - Springer
Background Some microbiota compositions are associated with negative outcomes,
including among others, obesity, allergies, and the failure to respond to treatment …

[HTML][HTML] Regulation, risk and safety of faecal microbiota transplant

B Merrick, L Allen, NMM Zain, B Forbes… - Infection prevention in …, 2020 - Elsevier
From its origins as a left-field, experimental, and even “maverick” intervention, faecal
microbiota transplantation (FMT) is now a well-recognised, accepted, and potentially life …

Challenges and costs of donor screening for fecal microbiota transplantations

MV Bénard, CMA de Bruijn, AC Fenneman… - PLoS …, 2022 - journals.plos.org
Background The increasing interest to perform and investigate the efficacy of fecal
microbiota transplantation (FMT) has generated an urge for feasible donor screening. We …

The evolving landscape of fecal microbial transplantation

T Shao, R Hsu, C Hacein-Bey, W Zhang, L Gao… - Clinical Reviews in …, 2023 - Springer
The human gastrointestinal tract houses an enormous microbial ecosystem. Recent studies
have shown that the gut microbiota plays significant physiological roles and maintains …

From donor to patient: collection, preparation and cryopreservation of fecal samples for fecal microbiota transplantation

C Nicco, A Paule, P Konturek, M Edeas - Diseases, 2020 - mdpi.com
Fecal Microbiota Transplantation (FMT) is suggested as an efficacious therapeutic strategy
for restoring intestinal microbial balance, and thus for treating disease associated with …