Advances in liposomal drug delivery to cancer: An overview

S Saraf, A Jain, A Tiwari, A Verma, PK Panda… - Journal of drug delivery …, 2020 - Elsevier
Liposomes are biodegradable and biocompatible lipid bilayer vesicles which are widely
exploited as preferred carriers for smart delivery of both hydrophobic as well as hydrophilic …

Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

J Ciccolini, C Serdjebi, GJ Peters… - Cancer chemotherapy and …, 2016 - Springer
Gemcitabine is an antimetabolite ranking among the most prescribed anticancer drugs
worldwide. This nucleoside analog exerts its antiproliferative action after tumoral conversion …

[HTML][HTML] Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy

G Pasut, D Paolino, C Celia, A Mero, AS Joseph… - Journal of controlled …, 2015 - Elsevier
Pegylation of nanoparticles has been widely implemented in the field of drug delivery to
prevent macrophage clearance and increase drug accumulation at a target site. However …

Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells

C Celia, E Trapasso, M Locatelli, M Navarra… - Colloids and Surfaces B …, 2013 - Elsevier
Citrus extracts, particularly bergamot essential oil (BEO) and its fractions, have been found
to exhibit anticancer efficacy. However, the poor water solubility, low stability and limited …

Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma

D Cosco, F Cilurzo, J Maiuolo, C Federico… - Scientific reports, 2015 - nature.com
The encapsulation of miR-34a into chitosan/PLGA nanoparticles in order to obtain
nanoplexes useful for the modulation of the biopharmaceutical features of the active …

Review of computer simulations on anti-cancer drug delivery in MOFs

M Kotzabasaki, GE Froudakis - Inorganic Chemistry Frontiers, 2018 - pubs.rsc.org
Metal–organic frameworks (MOFs) have been recently used as potential nanocarrier
platforms in biomedical applications such as drug storage and delivery, due to their low …

Development of liposomal gemcitabine with high drug loading capacity

H Tamam, J Park, HH Gadalla, AR Masters… - Molecular …, 2019 - ACS Publications
Liposomes are widely used for systemic delivery of chemotherapeutic agents to reduce their
nonspecific side effects. Gemcitabine (Gem) makes a great candidate for liposomal …

Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR®: biodistribution, pharmacokinetic features and in vivo antitumor activity

D Paolino, D Cosco, L Racanicchi, E Trapasso… - Journal of Controlled …, 2010 - Elsevier
The systemic efficacy of the chemotherapeutic agents presently used to treat solid tumors is
limited by their low therapeutic index. Previously, our research group improved the in vitro …

Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review

DF Silva, ALP Melo, AFC Uchôa, GMA Pereira… - International Journal of …, 2023 - mdpi.com
Nanotechnology has played a prominent role in biomedical engineering, offering innovative
approaches to numerous treatments. Notable advances have been observed in the …

Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response

D Cosco, D Paolino, F De Angelis, F Cilurzo… - European journal of …, 2015 - Elsevier
Abstract Novel PEGylated PLA nanocapsules (PEG-AcPLA nanocapsules), loading high
percentage of water soluble drugs have been formulated by using multiple emulsion …