Mouse models of chronic lymphocytic leukemia and Richter transformation: what we have learnt and what we are missing
MTS Bertilaccio, SS Chen - Frontiers in Immunology, 2024 - frontiersin.org
Although the chronic lymphocytic leukemia (CLL) treatment landscape has changed
dramatically, unmet clinical needs are emerging, as CLL in many patients does not respond …
dramatically, unmet clinical needs are emerging, as CLL in many patients does not respond …
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL
JA Eken, MT Koning, K Kupcova… - Journal of Experimental …, 2024 - rupress.org
Diffuse large B cell lymphoma of activated B cell type (ABC-DLBCL), a major cell-of-origin
DLBCL subtype, is characterized by chronic active B cell receptor (BCR) signaling and NF …
DLBCL subtype, is characterized by chronic active B cell receptor (BCR) signaling and NF …
Mouse models of CLL: in vivo modeling of disease initiation, progression, and transformation to Richter transformation
SS Chen - Seminars in Hematology, 2024 - Elsevier
Chronic lymphocytic leukemia (CLL) is a highly complex disease characterized by the
proliferation of CD5+ B cells in lymphoid tissues. Current modern treatments have brought …
proliferation of CD5+ B cells in lymphoid tissues. Current modern treatments have brought …
[HTML][HTML] Prehistory of chronic lymphocytic leukemia: clues from the B-cell receptor
F Davi - Haematologica, 2024 - ncbi.nlm.nih.gov
In this issue of Haematologica, Quinten et al. provide new insights into the early steps of the
development of chronic lymphocytic leukemia (CLL). 1 Following its initial description in …
development of chronic lymphocytic leukemia (CLL). 1 Following its initial description in …