The impact of transfusing fresher vs older red blood cells (RBCs) on patient-important
outcomes remains controversial. Two recently published large trials have provided new …

Erythrocyte osmotic fragility is a laboratory test which evaluates the stability of the
erythrocyte membrane to osmotic stress. The aim of this review is to highlight research …

Background During storage, red blood cells (RBCs) undergo significant biochemical and
morphologic changes, referred to collectively as the “storage lesion”. It was hypothesized …

Red blood cells (RBCs) collected for transfusion deteriorate during storage. This
deterioration is termed the “RBC storage lesion.” There is increasing concern over the …

Background Most frequent red cell (RBC) donors and many first-time donors are iron
deficient, but meet haemoglobin standards. However, the effects of donation-induced iron …

Background: To investigate the extent of oxidative damage and changes in morphology of
manually isolated red blood cells (RBCs) from whole blood, cold stored (up to 20 days) in …

Oxidative damage by free radicals has a negative effect on blood quality during storage.
Antioxidant nanoparticles can prevent oxidative stress. We use SOD‐CAT‐Alb‐PEG‐PLGA …

Background Despite fulfilling all requirements for blood donation, a large proportion of
regular blood donors are iron deficient. Red blood cells (RBC) from iron-deficient donors …

Background: Blood is permanently exposed to oxidation stress and therefore has a high
antioxidants capacity. Many different factors increasing the demand for the antioxidant …

BACKGROUND: The RBCs storage lesion is most carefully viewed as the sum of all the
changes in RBCs occurring during the course of storage and that limit their survival …