The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Due to the high surface: volume ratio and the extraordinary properties arising from the
nanoscale (optical, electric, magnetic, etc.), nanoparticles (NPs) are excellent candidates for …

Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Delivery and toxicity are critical issues facing nanomedicine research. Currently, there is
limited understanding and connection between the physicochemical properties of a …

Nanomaterials hold promise as multifunctional diagnostic and therapeutic agents. However,
the effective application of nanomaterials is hampered by limited understanding and control …

Nanoparticles are suitable platforms for cancer targeting and diagnostic applications.
Typically, less than 10% of all systemically administered nanoparticles accumulate in the …

Over the last few decades, nanocarriers for drug delivery have emerged as powerful tools
with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many …

Devices that function in contact with blood are ubiquitous in clinical medicine and
biotechnology. These devices include vascular grafts, coronary stents, heart valves …

Upon contact with plasma or other protein-containing biological fluids, the surface of
nanoparticles is immediately decorated with proteins forming a biologically active protein …

This article focuses on one of the major failure routes of implanted medical devices, the
foreign body reaction (FBR)—that is, the phagocytic attack and encapsulation by the body of …