Insulin-like growth factors (IGFs) bind specifically to the IGF1 receptor on the cell surface of
targeted tissues. Ligand binding to the α subunit of the receptor leads to a conformational …

Although the roots of Ras sprouted from the rich history of retrovirus research, it was the
discovery of mutationally activated RAS genes in human cancer in 1982 that stimulated an …

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …

Recent epidemiologic studies implying differences in cancer recurrence based on
anesthetic regimens raise the possibility that the mu opioid receptor (MOR) can influence …

Hepatocellular carcinoma (HCC) has emerged as one of the most common malignancies
worldwide. It is associated with a high mortality rate, as evident from its increasing incidence …

Growth factor and cytokine signaling can influence the development of several cancer types.
One of the key players in the development of cancer is the Janus kinas (JAK) signal …

Some of the intrinsically disordered proteins and protein regions are promiscuous
interactors that are involved in one-to-many and many-to-one binding. Several studies have …

Metastasis is one of the most important factors related to breast cancer therapeutic efficacy.
Ursolic acid, a naturally occurring triterpenoid, has various anticancer activities. In this study …

Simple Summary This review summarizes the current DUBs findings that correlate with the
most common cancers in the world (liver, breast, prostate, colorectal, pancreatic, and lung …

Lactoferrin (Lf) is a sialic acid (Sia)-rich, iron-binding milk glycoprotein that has
multifunctional health benefits. Its potential role in neurodevelopment and cognition remains …