The precise function of eosinophils in parasitic infection in vivo remains poorly understood
despite eosinophils having been shown to be potent effectors in killing parasites in vitro …

Eosinophils have been shown to be potent effector cells for the killing of helminth parasites
in in vitro cultures. However, an in vivo role for eosinophils has been more difficult to …

Eosinophilia–an increase in the number of eosinophils in the blood or tissues–has
historically been recognized as a distinctive feature of helminth infections in mammals. Yet …

The discovery of Wolbachia intracellular bacteria within filarial nematodes, including
Onchocerca volvulus, the causative agent of onchocerciasis or “river blindness,” has …

Since the earliest descriptions of this enigmatic cell, eosinophils have been implicated in
both protective and pathogenic immune responses to helminth infection. Nevertheless …

Onchocerca volvulus is a tissue-invasive parasitic nematode causing skin and eye
pathology in human onchocerciasis. The filariae habour abundant intracellular Wolbachia …

Although TH2 cytokine involvement in allergy makes these cytokines attractive therapeutic
targets, they protect against ectoparasites and gastrointestinal worms and suppress …

Eosinophils have previously been shown to accumulate around the tissue invasive (L3)
stage of sheep gastrointestinal parasites in vivo. In this study, eosinophils obtained from …

Neutrophils are key components of the inflammatory response and as such contribute to the
killing of microorganisms. In addition, recent evidence suggests their involvement in the …

Background Polymorphonuclear neutrophil (PMN) and eosinophil extracellular trap (ETs)
formation has recently been described as an important host effector mechanism against …