In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
α‐glucosidase, α‐amylase inhibition, kinetics and docking studies of novel (2‐chloro‐6‐(trifluoromethyl) benzyloxy) arylidene) based rhodanine and rhodanine acetic …
V Kumar, R Ramu, PS Shirahatti, VBC Kumari… - …, 2021 - Wiley Online Library
In our effort to identify potent fluorinated small molecules as antidiabetic compounds, a novel
fluorinated series of 2‐chloro‐6‐(trifluoromethyl) benzyloxy arylidene derived Rhodanine …
fluorinated series of 2‐chloro‐6‐(trifluoromethyl) benzyloxy arylidene derived Rhodanine …
Isatin: New hope against convulsion
RS Cheke, SD Firke, RR Patil… - Central Nervous System …, 2018 - ingentaconnect.com
Background: Epilepsy is one in every of the foremost important chronic neurological
disorders with high incidence worldwide. Several epileptic patients don't seem to be fully …
disorders with high incidence worldwide. Several epileptic patients don't seem to be fully …
Potential Fluorinated Anti‐MRSA Thiazolidinone Derivatives with Antibacterial, Antitubercular Activity and Molecular Docking Studies
V Kumar, P Shetty, A HS, S Chandra K… - Chemistry & …, 2022 - Wiley Online Library
MRSA infection is one of the alarming diseases in the current scenario. Identifying newer
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …
Synthesis, molecular docking, antibacterial, and anti‐inflammatory activities of benzimidazole‐containing tricyclic systems
In the present study, we reported the synthesis of benzimidazole‐containing tricyclic systems
and evaluated their antimicrobial efficacy against some Gram‐positive, Gram‐negative …
and evaluated their antimicrobial efficacy against some Gram‐positive, Gram‐negative …
[HTML][HTML] Design, synthesis, docking, and antidepressant activity evaluation of isatin derivatives bearing Schiff bases
A Mesripour, E Jafari, MR Hajibeiki… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Depression is a prevalent psychiatric disorder. Treatment of depression is still
a challenge due to the lack of response of some patients to a variety of available …
a challenge due to the lack of response of some patients to a variety of available …
[HTML][HTML] Prediction of lipophilicity and pharmacokinetics of chloroacetamides by chemometric approach
G Vastag, S Apostolov, B Matijević - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
In this study, the existence of biological potential of selected N-(substituted phenyl)-2-
chloroacetamides was examined none empirically, as was the possibility of applying simple …
chloroacetamides was examined none empirically, as was the possibility of applying simple …
Chromatographic and Computational Assessment of Potential Biological Activity of N-(Substituted Phenyl)- 2-Chloroacetamides Applying Multivariate Methods
S Apostolov, G Vastag, B Matijević… - Journal of Liquid …, 2015 - Taylor & Francis
The lipophilicity of the newly synthesized N-(substituted phenyl)-2-chloroacetamides, as the
most commonly used molecular descriptor of a potential biological activity was the subject of …
most commonly used molecular descriptor of a potential biological activity was the subject of …
Structure‐interaction relationship study of N‐(4‐phenylsubstituted) cyanoacetamides by multivariate methods
G Vastag, S Apostolov, B Matijević… - Journal of …, 2016 - Wiley Online Library
Derivatives of amides belong to a very attractive group of compounds due to a broad
spectrum of different biological activities. The type of molecule activity significantly depends …
spectrum of different biological activities. The type of molecule activity significantly depends …
[HTML][HTML] 基于咔唑-三嗪并吲哚的N-酰腙衍生物的NMR数据归属
李英俊, 杨鸿境, 刘季红, 靳焜, 林乐弟, 刘雪洁 - 波谱学杂志, 2020 - html.rhhz.net
N-酰腙类化合物在极性溶剂中存在着E/cis 和E/trans 两种异构体, 本文利用元素分析, 红外光谱,
1D 和2D 核磁共振(NMR) 波谱(包括1 H NMR, 13 C NMR, 1 H-1 H COSY, 1 H-13 C HSQC, 1 …
1D 和2D 核磁共振(NMR) 波谱(包括1 H NMR, 13 C NMR, 1 H-1 H COSY, 1 H-13 C HSQC, 1 …