Cryptosporidium pathogenicity and virulence
M Bouzid, PR Hunter, RM Chalmers… - Clinical microbiology …, 2013 - Am Soc Microbiol
Cryptosporidium is a protozoan parasite of medical and veterinary importance that causes
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …
Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications
A Herreros-Cabello, F Callejas-Hernández, N Gironès… - Genes, 2020 - mdpi.com
Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
Multigene families in Trypanosoma cruzi and their role in infectivity
LM De Pablos, A Osuna - Infection and immunity, 2012 - Am Soc Microbiol
The Trypanosoma cruzi genome contains the most widely expanded content (∼ 12,000
genes) of the trypanosomatids sequenced to date. This expansion is reflected in the high …
genes) of the trypanosomatids sequenced to date. This expansion is reflected in the high …
Genomic assemblies of newly sequenced Trypanosoma cruzi strains reveal new genomic expansion and greater complexity
Chagas disease is a complex illness caused by the protozoan Trypanosoma cruzi
displaying highly diverse clinical outcomes. In this sense, the genome sequence elucidation …
displaying highly diverse clinical outcomes. In this sense, the genome sequence elucidation …
Genomic Analyses, Gene Expression and Antigenic Profile of the Trans-Sialidase Superfamily of Trypanosoma cruzi Reveal an Undetected Level of Complexity
LM Freitas, SL Dos Santos, GF Rodrigues-Luiz… - Plos one, 2011 - journals.plos.org
The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a
highly debilitating human pathology that affects millions of people in the Americas. The …
highly debilitating human pathology that affects millions of people in the Americas. The …
Genome evolution in trypanosomatid parasites
AP Jackson - Parasitology, 2015 - cambridge.org
A decade of genome sequencing has transformed our understanding of how trypanosomatid
parasites have evolved and provided fresh impetus to explaining the origins of parasitism in …
parasites have evolved and provided fresh impetus to explaining the origins of parasitism in …
Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi
Trypanosoma cruzi, a zoonotic kinetoplastid protozoan parasite, is the causative agent of
American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex …
American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex …
Telomere and subtelomere R-loops and antigenic variation in trypanosomes
Trypanosoma brucei is a kinetoplastid parasite that causes African trypanosomiasis, which
is fatal if left untreated. T. brucei regularly switches its major surface antigen, VSG, to evade …
is fatal if left untreated. T. brucei regularly switches its major surface antigen, VSG, to evade …
Mechanisms of adaptation and evolution in Toxoplasma gondii
Toxoplasma has high host flexibility, infecting all nucleated cells of mammals and birds. This
implies that during its infective process the parasite must constantly adapt to different …
implies that during its infective process the parasite must constantly adapt to different …
Anatomy and evolution of telomeric and subtelomeric regions in the human protozoan parasite Trypanosoma cruzi
RR Moraes Barros, MM Marini, CR Antônio, DR Cortez… - BMC genomics, 2012 - Springer
Background The subtelomeres of many protozoa are highly enriched in genes with roles in
niche adaptation. T. cruzi trypomastigotes express surface proteins from Trans-Sialidase …
niche adaptation. T. cruzi trypomastigotes express surface proteins from Trans-Sialidase …