Macrophage heterogeneity in tissues: phenotypic diversity and functions

S Gordon, A Plüddemann… - Immunological …, 2014 - Wiley Online Library
During development and throughout adult life, macrophages derived from hematopoietic
progenitors are seeded throughout the body, initially in the absence of inflammatory and …

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

TA Springer - Cell, 1994 - Elsevier
Multiple protein families, each with a distinct function, provide the traffic signals for
leukocytes. The selectin family of adhesion molecules (Figure 2) has an N-terminal domain …

[HTML][HTML] A physical wiring diagram for the human immune system

J Shilts, Y Severin, F Galaway, N Müller-Sienerth… - Nature, 2022 - nature.com
The human immune system is composed of a distributed network of cells circulating
throughout the body, which must dynamically form physical associations and communicate …

Mpox vaccine and infection-driven human immune signatures: an immunological analysis of an observational study

H Cohn, N Bloom, GY Cai, JJ Clark, A Tarke… - The Lancet Infectious …, 2023 - thelancet.com
Background Monkeypox virus has recently infected more than 88 000 people, raising
concerns about our preparedness against this emerging viral pathogen. Licensed and …

Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury

T Ichimura, JV Bonventre, V Bailly, H Wei… - Journal of Biological …, 1998 - ASBMB
We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named …

AC133, a novel marker for human hematopoietic stem and progenitor cells

AH Yin, S Miraglia, ED Zanjani… - Blood, The Journal …, 1997 - ashpublications.org
AC133 is one of a new panel of murine hybridoma lines producing monoclonal IgG
antibodies (mAbs) to a novel stem cell glycoprotein antigen with a molecular weight of 120 …

Medical application of functionalized magnetic nanoparticles

A Ito, M Shinkai, H Honda, T Kobayashi - Journal of bioscience and …, 2005 - Elsevier
Since magnetic particles have unique features, the development of a variety of medical
applications has been possible. The most unique feature of magnetic particles is their …

Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes

A Bouchon, J Dietrich, M Colonna - The Journal of Immunology, 2000 - journals.aai.org
We have identified new activating receptors of the Ig superfamily expressed on human
myeloid cells, called TREM (triggering receptor expressed on myeloid cells). TREM-1 is …

Biological and clinical significance of haptoglobin polymorphism in humans

MR Langlois, JR Delanghe - Clinical chemistry, 1996 - academic.oup.com
Haptoglobin is a hemoglobin-binding protein expressed by a genetic polymorphism as three
major phenotypes: 1-1, 2-1, and 2-2. Most attention has been paid to determining …

Concepts and principles of O-linked glycosylation

PV Steen, PM Rudd, RA Dwek… - Critical reviews in …, 1998 - Taylor & Francis
The biosynthesis, structures, and functions of O-glycosylation, as a complex
posttranslational event, is reviewed and compared for the various types of O-glycans. Mucin …