Despite advances in neurosurgical techniques and radio-/chemotherapy, the treatment of
brain tumors remains a challenge. This is particularly true for the most frequent and fatal …

Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

Purpose: High-grade gliomas are associated with a dismal prognosis. Notch inhibition via
the gamma-secretase inhibitor RO4929097 has emerged as a potential therapeutic option …

Human papillomavirus driven head and neck squamous cell carcinoma (HNSCC),
particularly oropharyngeal squamous cell carcinoma (OPSCC), are characterized by a …

Glioblastoma stem cells (GSCs) are cells with a self-renewal ability and capacity to initiate
tumors upon serial transplantation that have been linked to tumor cell heterogeneity. Most …

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The
current standard of care includes surgery followed by radiotherapy (RT) and chemotherapy …

Background Oral squamous cell carcinoma (OSCC) is a malignant oral cavity neoplasm that
affects many people, especially in developing countries. Despite several advances that have …

The current therapeutic protocols and prognosis of gliomas still depend on clinicopathologic
and radiographic characteristics. For high-grade gliomas, the standard of care is resection …

Thyroid cancer is the most common malignancy of the endocrine system with a steadily
rising incidence. The term “thyroid cancer” encompasses a spectrum of subtypes, namely …