Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS)
through its metabolites. This process leads to steatosis and liver inflammation, which are …

Cellular senescence, a process in which a cell exits the cell cycle in response to stressors, is
one of the hallmarks of aging. Senescence and the senescence-associated secretory …

Endoplasmic reticulum (ER) is the site for synthesis and folding of secreted and
transmembrane proteins. Disturbance in the functioning of ER leads to the accumulation of …

Autophagy is a vital cellular mechanism that benefits cellular maintenance and survival
during cell stress. It can eliminate damaged or long-lived organelles and improperly folded …

The endoplasmic reticulum (ER) plays a pivotal role in protein synthesis, folding, and
modification. Under stress conditions such as oxidative stress and inflammation, the ER can …

Autophagy is an essential quality control mechanism for maintaining organellar functions in
eukaryotic cells. Defective autophagy in pancreatic beta cells has been shown to be …

Autophagy is a highly conserved process in which cytosolic contents are degraded by the
lysosome, which plays an important role in energy and nutrient balance, and protein or …

Alcoholic liver disease (ALD), a spectrum of liver abnormalities induced by chronic alcohol
abuse, continues to be the major cause of life-threatening liver disease in developed …

Introduction Ganshu Nuodan is a liver-protecting dietary supplement composed of
Ganoderma lucidum (G. lucidum) spore powder, Pueraria montana (Lour.) Merr.(P …

Extracellular vesicles (EVs) are important mediators of intercellular communication in the
tumour microenvironment. Many studies suggest that cancer cells release higher amounts of …