Microbial nanowires for sustainable electronics
MJ Guberman-Pfeffer, NM Dorval Courchesne… - Nature Reviews …, 2024 - nature.com
Microbial protein nanowires are emerging as an alternative to abiotic nanowires for
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …
Artificial metalloenzymes
T Vornholt, F Leiss-Maier, WJ Jeong… - Nature Reviews …, 2024 - nature.com
The development of artificial metalloenzymes (ArMs) aims to expand the capabilities of
enzymatic catalysis, most notably towards new reaction mechanisms. Frequently, ArMs …
enzymatic catalysis, most notably towards new reaction mechanisms. Frequently, ArMs …
Delineating redox cooperativity in water‐soluble and membrane multiheme cytochromes through protein design
BJ Hardy, P Dubiel, EL Bungay, M Rudin… - Protein …, 2024 - Wiley Online Library
Nature has evolved diverse electron transport proteins and multiprotein assemblies
essential to the generation and transduction of biological energy. However, substantially …
essential to the generation and transduction of biological energy. However, substantially …
Exo-chirality of the α-helix
JM Martínez-Parra, R Gómez-Ojea, GA Daudey… - Nature …, 2024 - nature.com
The structure of helical polymers is dictated by the molecular chirality of their monomer units.
Particularly, macromolecular helices with monomer sequence control have the potential to …
Particularly, macromolecular helices with monomer sequence control have the potential to …
Fluctuation relations to calculate protein redox potentials from molecular dynamics simulations
The tunable design of protein redox potentials promises to open a range of applications in
biotechnology and catalysis. Here, we introduce a method to calculate redox potential …
biotechnology and catalysis. Here, we introduce a method to calculate redox potential …
[HTML][HTML] Building tailor-made bioenergetic proteins and circuits from de novo redox proteins
BJ Hardy, EL Bungay, C Mellor, P Curnow… - Current Opinion in …, 2024 - Elsevier
Natural electron-conducting circuits play essential roles in respiration and photosynthesis
and are therefore of fundamental importance to all life on earth. These circuits are composed …
and are therefore of fundamental importance to all life on earth. These circuits are composed …
Development of artificial photosystems based on designed proteins for mechanistic insights into photosynthesis
This review aims to provide an overview of the progress in protein‐based artificial
photosystem design and their potential to uncover the underlying principles governing light …
photosystem design and their potential to uncover the underlying principles governing light …
Computational design of de novo bioenergetic membrane proteins
BJ Hardy, P Curnow - Biochemical Society Transactions, 2024 - portlandpress.com
The major energy-producing reactions of biochemistry occur at biological membranes.
Computational protein design now provides the opportunity to elucidate the underlying …
Computational protein design now provides the opportunity to elucidate the underlying …
Confinement and Catalysis Within De Novo Designed Peptide Barrels
R Petrenas, OA Hawkins, JF Jones, DA Scott… - bioRxiv, 2024 - biorxiv.org
De novo protein design has advanced such that many peptide assemblies and protein
structures can be generated predictably and quickly. The drive now is to bring functions to …
structures can be generated predictably and quickly. The drive now is to bring functions to …
Protein dynamics govern the oxyferrous state lifetime of an artificial oxygen transport protein
L Zhang, MC Brown, AC Mutter, KN Greenland… - Biophysical …, 2023 - cell.com
It has long been known that the alteration of protein side chains that occlude or expose the
heme cofactor to water can greatly affect the stability of the oxyferrous heme state. Here, we …
heme cofactor to water can greatly affect the stability of the oxyferrous heme state. Here, we …