Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Quantitative phase imaging in biomedicine

YK Park, C Depeursinge, G Popescu - Nature photonics, 2018 - nature.com
Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …

Live-cell mass profiling: an emerging approach in quantitative biophysics

TA Zangle, MA Teitell - Nature methods, 2014 - nature.com
Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …

Quantitative 3D refractive index tomography of opaque samples in epi-mode

P Ledwig, FE Robles - Optica, 2020 - opg.optica.org
Three-dimensional (3D) refractive index (RI) tomography has recently become an exciting
new tool for biological studies. However, its limitation to (1) thin samples resulting from a …

Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers …

P Marquet, C Depeursinge, PJ Magistretti - Neurophotonics, 2014 - spiedigitallibrary.org
Quantitative phase microscopy (QPM) has recently emerged as a new powerful quantitative
imaging technique well suited to noninvasively explore a transparent specimen with a …

Quantitative phase imaging based on holography: trends and new perspectives

Z Huang, L Cao - Light: Science & Applications, 2024 - nature.com
Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …

Optical phase measurements of disorder strength link microstructure to cell stiffness

WJ Eldridge, ZA Steelman, B Loomis, A Wax - Biophysical journal, 2017 - cell.com
There have been sustained efforts on the part of cell biologists to understand the
mechanisms by which cells respond to mechanical stimuli. To this end, many rheological …

Imaging deformation of adherent cells due to shear stress using quantitative phase imaging

WJ Eldridge, A Sheinfeld, MT Rinehart, A Wax - Optics letters, 2016 - opg.optica.org
We present a platform for detecting cellular deformations from mechanical stimuli, such as
fluid shear stress, using rapid quantitative phase imaging. Rapid quantitative phase imaging …

Exploring neural cell dynamics with digital holographic microscopy

P Marquet, C Depeursinge… - Annual review of …, 2013 - annualreviews.org
In this review, we summarize how the new concept of digital optics applied to the field of
holographic microscopy has allowed the development of a reliable and flexible digital …

Recent progress in lab-on-a-chip systems for the monitoring of metabolites for mammalian and microbial cell research

E Dervisevic, KL Tuck, NH Voelcker, VJ Cadarso - Sensors, 2019 - mdpi.com
Lab-on-a-chip sensing technologies have changed how cell biology research is conducted.
This review summarises the progress in the lab-on-a-chip devices implemented for the …