Although a normal karyotype according to conventional cytogenetic analysis in association
with cryptic t (15; 17) has been infrequently reported in cases of acute promyelocytic …

Acute myeloid leukemia is the most common type of leukemia in adults, yet it continues to
have the lowest survival rate of all leukemias. Prognosis for the elderly in particular …

We studied the immunophenotype of 100 cases of acute promyelocytic leukemia (APL) with
cytogenetic evidence of t (15; 17)(q22; q21), 72 hypergranular (M3) and 28 microgranular …

Results Ninety-seven cases of APL with t (15; 17)/PML-RARA confirmed by conventional
cytogenetics and/or FISH studies were analyzed for FC immunophenotypic features. The …

This third edition is the product of the author's 25 years of experience with flow cytometry;
although it covers the wide spectrum of hematopoietic tumors, the focus remains on most …

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation, t (15;
17)(q22; q12), resulting in fusion of the genes promyelocytic leukemia (PML) and retinoic …

This atlas presents not only the differential diagnosis but also the detailed morphologic,
immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid …

Acute promyelocytic leukemia (APL) is characterized by the presence of rearrangements
involving the retinoic acid receptor α (RARα) gene and a variable incidence in different …

A leucemia promielocítica aguda (LPA) corresponde a 10%-15% das leucemias mielóides
agudas (LMA). Este tipo de leucemia (LMA-M3 de acordo com a classificação FAB) está …

Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially
polymerase chain reaction (PCR), play an important role in the management of patients with …