Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019 - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Advances in injectable hydrogel strategies for heart failure treatment

S He, Z Zhang, R Luo, Q Jiang, L Yang… - Advanced Healthcare …, 2023 - Wiley Online Library
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …

[HTML][HTML] The platelet response to tissue injury

F Eisinger, J Patzelt, HF Langer - Frontiers in medicine, 2018 - frontiersin.org
In recent years, various studies have increasingly explained platelet functions not only in
their central role as a regulator in cellular hemostasis and coagulation. In fact, there is …

Patient‐specific bioinks for 3D bioprinting of tissue engineering scaffolds

N Faramarzi, IK Yazdi, M Nabavinia… - Advanced …, 2018 - Wiley Online Library
Bioprinting has emerged as a promising tool in tissue engineering and regenerative
medicine. Various 3D printing strategies have been developed to enable bioprinting of …

An injectable chitosan/dextran/β-glycerophosphate hydrogel as cell delivery carrier for therapy of myocardial infarction

X Ke, M Li, X Wang, J Liang, X Wang, S Wu… - Carbohydrate …, 2020 - Elsevier
Acute myocardial infarction (MI) is a common cardiovascular disease with high mortality. In
this study, an injectable thermosensitive hydrogel of chitosan (CS)/dextran (DEX)/β …

[HTML][HTML] Encapsulation of lyophilized platelet-rich fibrin in alginate-hyaluronic acid hydrogel as a novel vascularized substitution for myocardial infarction

B Qian, Q Yang, M Wang, S Huang, C Jiang, H Shi… - Bioactive materials, 2022 - Elsevier
Cardiovascular diseases such as myocardial infarction (MI) are among the major causes of
death worldwide. Although intramyocardial injection of hydrogels can effectively enhance …

Antifibrotic therapies to control cardiac fibrosis

Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …

[HTML][HTML] Role of platelet rich plasma mediated repair and regeneration of cell in early stage of cardiac injury

SS Imam, FA Al-Abbasi, S Hosawi, M Afzal… - Regenerative …, 2022 - Elsevier
Platelet-rich plasma (PRP) is a widely accepted treatment approach and has heightened the
quality of care among physicians. PRP has been used over the last decade to boost clinical …

[HTML][HTML] Systemic mesenchymal stem cell-derived exosomes reduce myocardial infarct size: characterization with MRI in a porcine model

CJ Charles, RR Li, T Yeung, SMI Mazlan… - Frontiers in …, 2020 - frontiersin.org
The observations that mesenchymal stem cells (MSCs) exert cardiac protection and repair
via their secretome with the active component (s) identified as exosomes underpinned our …

Applications of biomaterials for immunosuppression in tissue repair and regeneration

P Shen, Y Chen, S Luo, Z Fan, J Wang, J Chang… - Acta Biomaterialia, 2021 - Elsevier
The immune system plays an essential role in tissue repair and regeneration. Regardless of
innate or adaptive immune responses, immunosuppressive strategies such as macrophage …