Habituation to a novel environment in rodents is commonly defined as a change in
exploratory or locomotor activity over time (intrasession) or with repeated exposures …

Cognition in transgenic and knockout mice is preferentially assessed by spatial learning in
the Morris water maze. Awareness is growing, however, that the putative cognitive deficits …

A two-trial memory task, based on a free-choice exploration paradigm in a Y-maze, was
previously developed to study recognition processes in Sprague-Dawley rats. Because this …

Episodic memory refers to the conscious recollection of a unique past experience in terms of
“what” happened and “where” and “when” it happened. Since deficits in episodic memory …

The relationship between FOS production in the sensory cortex and limbic system and the
ability of C57BL/6N mice to acquire context-and tone-dependent freezing were investigated …

The present studies examined sex differences in object localization and recognition in
C57BL/6 mice. Experiment 1 measured responses to spatial novelty (object displacement) …

Background Attentional dysfunction is related to functional disability in patients with
neuropsychiatric disorders such as schizophrenia, bipolar disorder, and Alzheimer's …

To determine if there is genetic variability in habituation of activity in an open field, we
examined a number of inbred strains and F 1 hybrids. Using 5-min exposures to a dark open …

We have mapped intracortical activity in vivo independent of sensory input using arbitrary
point channelrhodopsin-2 (ChR2) stimulation and regional voltage sensitive dye imaging in …

Induction of long‐term depression (LTD) in rat striatal slices revealed that this form of
synaptic plasticity is coupled to an increased expression of tissue‐plasminogen activator (t …