Synaptic degeneration in Alzheimer disease
Alzheimer disease (AD) is characterized by progressive cognitive decline in older
individuals accompanied by the presence of two pathological protein aggregates—amyloid …
individuals accompanied by the presence of two pathological protein aggregates—amyloid …
A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
Comprehensive review on Alzheimer's disease: causes and treatment
Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a disorder that causes degeneration of the cells in the brain and
it is the main cause of dementia, which is characterized by a decline in thinking and …
it is the main cause of dementia, which is characterized by a decline in thinking and …
Alzheimer's disease and its treatment by different approaches: A review
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …
development and interrupts neurocognitive function. This neuropathological condition is …
Extrasynaptic NMDA receptors in acute and chronic excitotoxicity: implications for preventive treatments of ischemic stroke and late-onset Alzheimer's disease
SP Yu, MQ Jiang, SS Shim, S Pourkhodadad… - Molecular …, 2023 - Springer
Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …
comorbidity of these brain disorders in aging individuals represents a significant challenge …
The synapse as a treatment avenue for Alzheimer's Disease
L Peng, I Bestard-Lorigados, W Song - Molecular psychiatry, 2022 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disorder with devastating symptoms,
including memory impairments and cognitive deficits. Hallmarks of AD pathology are …
including memory impairments and cognitive deficits. Hallmarks of AD pathology are …
Glymphatic system, AQP4, and their implications in Alzheimer's disease
I Silva, J Silva, R Ferreira, D Trigo - Neurological research and practice, 2021 - Springer
Lacking conventional lymphatic system, the central nervous system requires alternative
clearance systems, such as the glymphatic system, which promotes clearance of interstitial …
clearance systems, such as the glymphatic system, which promotes clearance of interstitial …
ESO Guideline on covert cerebral small vessel disease
JM Wardlaw, S Debette, H Jokinen… - European Stroke …, 2021 - journals.sagepub.com
'Covert'cerebral small vessel disease (ccSVD) is common on neuroimaging in persons
without overt neurological manifestations, and increases the risk of future stroke, cognitive …
without overt neurological manifestations, and increases the risk of future stroke, cognitive …
The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Pharmacotherapy evolution in Alzheimer's disease: current framework and relevant directions
Alzheimer's disease (AD), once considered a rare disease, is now the most common form of
dementia in the elderly population. Current drugs (cholinesterase inhibitors and glutamate …
dementia in the elderly population. Current drugs (cholinesterase inhibitors and glutamate …