Bioactive peptides have been identified in a range of foods, including plant, milk and
muscle, eg, beef, chicken, pork and fish muscle proteins. Bioactive peptides from food …

With the advent of technologies to obtain the complete sequence of the human genome in a
cost-effective manner, this decade and those to come will see an exponential increase in our …

The talin-vinculin axis is a key mechanosensing component of cellular focal adhesions. How
talin and vinculin respond to forces and regulate one another remains unclear. By …

Active materials are capable of converting free energy into mechanical work to produce
autonomous motion, and exhibit striking collective dynamics that biology relies on for …

While the dynamin GTPase Drp1 plays a critical role during mitochondrial fission,
mechanisms controlling its recruitment to fission sites are unclear. A current assumption is …

The small GTPase Rho is implicated in physiological functions associated with actin-myosin
filaments such as cytokinesis, cell motility, and smooth muscle contraction. We have recently …

Blebbistatin is a recently discovered small molecule inhibitor showing high affinity and
selectivity toward myosin II. Here we report a detailed investigation of its mechanism of …

Publisher Summary This chapter explores some of the pitfalls associated with actin
purification and to clarify in some detail the correct use and expected result from each step of …

Active materials are capable of converting free energy into directional motion, giving rise to
notable dynamical phenomena. Developing a general understanding of their structure in …

I measured the rate of elongation at the barbed and pointed ends of actin filaments by
electron microscopy with Limulus sperm acrosomal processes as nuclei. With improvements …