It is now clear that vitamin D has important roles in addition to its classic effects on calcium
and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T …

Both 25-autoimmunity and (25 (OH) D: calcifediol) and its active form, 1, 25-dihydroxyvitamin
D (1, 25 (OH) 2D: calcitriol), play critical roles in protecting humans from invasive pathogens …

Objective To examine trends in the incidence and prevalence of rheumatoid arthritis (RA)
from 1995 to 2007. Methods To augment our preexisting inception cohort of patients with RA …

Vitamin D has received increased attention recently for its pleiotropic actions on many
chronic diseases. The importance of vitamin D on the regulation of cells of the immune …

Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …

Calcitriol, or 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) is a well-known endocrine regulator
of calcium homeostasis. More recently, local calcitriol production by immune cells was …

OBJECTIVE: To evaluate whether vitamin D levels are related to the risk of developing
autoimmune diseases and whether supplementation with vitamin D can modify the course of …

Lately, vitamin D has been linked with metabolic and immunological processes, which
established its role as an essential component of human health preservation. Vitamin D has …

Vitamin D has well-documented effects on calcium homeostasis and bone metabolism but
recent studies suggest a much broader role for this secosteroid in human health. Key …

Background Low serum vitamin D concentrations have been reported in several
autoimmune disorders. Objective To assess whether low serum vitamin D concentrations …