Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …

Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …

Aging and neurodegenerative diseases share common hallmarks, including mitochondrial
dysfunction and protein aggregation. Moreover, one of the major issues of the demographic …

Parkinson's disease is a neurological disorder with evolving layers of complexity. It has long
been characterised by the classical motor features of parkinsonism associated with Lewy …

Abstract Introduction We showed that Parkinson's disease (PD) patients have alpha‐
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …

This article reviews and summarizes 200 years of Parkinson's disease. It comprises a
relevant history of Dr. James Parkinson's himself and what he described accurately and …

With the growing awareness of the presence of non-motor symptoms in Parkinson's disease
(PD) has come the realization that these non-motor features play a tremendously important …

Under physiological conditions, the number and function of microglia—the resident
macrophages of the CNS—is tightly controlled by the local microenvironment. In response to …

Abstract See Nieuwhof and Helmich (doi: 10.1093/brain/awx267) for a scientific commentary
on this article. Parkinson's disease is a neurodegenerative disorder characterized by …