[HTML][HTML] Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?

C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …

[HTML][HTML] Herb and spices in colorectal cancer prevention and treatment: A narrative review

MS Hossain, MA Kader, KW Goh, M Islam… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the second most deadly cancer worldwide. CRC management is
challenging due to late detection, high recurrence rate, and multi-drug resistance. Herbs and …

The role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects

M Yuan, G Zhang, W Bai, X Han, C Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
Cancer is one of the greatest causes of death worldwide. With the development of surgery,
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …

Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer

W Liao, L Zhang, X Chen, J Xiang, Q Zheng, N Chen… - Phytomedicine, 2023 - Elsevier
Abstract Background Cancer stem cells (CSCs) are strongly associated with high
tumourigenicity, chemotherapy or radiotherapy resistance, and metastasis and recurrence …

Dietary phytochemicals modulate intestinal epithelial barrier dysfunction and autoimmune diseases

K Ganesan, JL Quiles, M Daglia, J Xiao, B Xu - Food Frontiers, 2021 - Wiley Online Library
The intestinal epithelium acts as a key defensive barrier that protects internal organs from
the detrimental gut environment. The homeostasis of the gut epithelium may be altered by …

The Antitriple Negative Breast cancer Efficacy of Spatholobus suberectus Dunn on ROS‐Induced Noncanonical Inflammasome Pyroptotic Pathway

F Zhang, Q Liu, K Ganesan, Z Kewu… - Oxidative Medicine …, 2021 - Wiley Online Library
Breast cancer (BCa) is the leading cause of women's death worldwide; among them, triple‐
negative breast cancer (TNBC) is one of the most troublesome subtypes with easy …

Effects and mechanisms of dietary bioactive compounds on breast cancer prevention

K Ganesan, B Du, J Chen - Pharmacological Research, 2022 - Elsevier
Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …

Updated review on green tea polyphenol epigallocatechin-3-gallate as a cancer epigenetic regulator

F Li, S Qasim, D Li, QP Dou - Seminars in Cancer Biology, 2022 - Elsevier
In-depth insights in cancer biology over the past decades have highlighted the important
roles of epigenetic mechanisms in the initiation and progression of tumorigenesis. The …

[HTML][HTML] Natural polyphenols for treatment of colorectal cancer

Y Zhang, K Liu, C Yan, Y Yin, S He, L Qiu, G Li - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

[HTML][HTML] Phenolic phytochemicals for prevention and treatment of colorectal cancer: A critical evaluation of in vivo studies

S De, S Paul, A Manna, C Majumder, K Pal, N Casarcia… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …