Background In traditional medicine whole plants or mixtures of plants are used rather than
isolated compounds. There is evidence that crude plant extracts often have greater in vitro …

Due to the promising features of the ancient herbal plant Artemisia, its biologic activity has
been investigated for use in modern medicine. In this regard, Artemisia and its active …

Malaria is an increasing worldwide threat, with more than three hundred million infections
and one million deaths every year. The worlds poorest are the worst affected, and many treat …

Abstract Oral administration of Chinese Herbal Medicine (CHM) faces various challenges in
reaching the target organs including absorption and conversion in the gastrointestinal tract …

Artemisinin has been used effectively in malaria treatment. With the emerging resistance to
malaria, the optimum and judicial use of the drug has become important. The drug …

Aim Our goal was to investigate whether artemisinin autoinduction is caused by an increase
in cytochrome P450 (CYP) 2B6 or CYP2C9 activities, we evaluated the effects of multiple …

There are several clinically useful endoperoxides, mainly artemisinin derivatives available in
market for the treatment of malaria. These are highly potent drugs, with fastest parasite …

Ethnopharmacological relevance The chemical matrix of the herb Artemisia annua L.(A.
annua), from which artemisinin (QHS) is isolated, can enhance both the bioavailability and …

Artemisinin‐hydroxychloroquine sulfate tablets (AH) are relatively inexpensive and a novel
combination therapy for the treatment of all forms of malaria, especially aminoquinine drug …

Background Artemisinin (a sesquiterpene lactone endoperoxide) has become important in
multi‐drug treatment of malaria. There is evidence that artemisinin induces drug metabolism …